Jay A. Tischfield, PhD, FFACMG
After graduating from the Scholar’s Program at Brooklyn College, Jay A. Tischfield received his M. Phil and Ph.D. degrees from Yale. As a postdoctoral fellow in the Department of Pediatrics at the University of California, San Francisco, he did the first molecular biology research on Down syndrome. He has held professorial appointments at Case Western Reserve, the Medical College of Georgia, Indiana University School of Medicine, and the University of Cincinnati College Of Medicine. Dr. Tischfield is MacMillan Professor and Chair of the Department of Genetics at Rutgers University, Professor of Psychiatry and Pediatrics at Robert Wood Johnson School of Medicine, and Executive Director of the Human Genetics Institute of New Jersey. His research interests diverge in two independent directions. On one hand, his laboratory studies loss of somatic cell alleles or allelic activity through recombinational, epigenetic andmutational mechanisms. Current focus is on specialized mechanisms for maintaining genomic integrity in embryonic stem cells and adult stem cells. On the other hand, he and members of his group focus on the genetics of complex human diseases with emphasis on the molecular genetics of mental disorders (autism, Tourette Syndrome), alcoholism, and opiate addiction. Dr. Tischfield is the Principal Investigator of active NIH awards in excess of $25 million per year, most of which are to provide facilities and infrastructural support for four NIH Institutes whose aim is establishing repositories and providing mechanisms for broad sharing cell lines, DNA, RNA, clinical and genotype data. Most commonly, NIH PIs send blood samples to the Rutgers University Cell and DNA Repository (RUCDR) for productionof lymphocyte cell lines; and DNA, RNA and other molecules are extracted from the original blood or derivative cell lines and analyzed (i.e., SNPs, gene copy number, and mRNA expression on chips as well as through qPCR). The group also conducts data analysis through statistical genetics approaches. Most studies supported by RUCDR focus on the genetics of “complex” diseases such as autism, schizophrenia, bipolar disorder, diabetes, inflammatory bowel disease, alcoholism and substance abuse. Dr. Tischfield is Co-Director of the NIMH Center for Collaborative Genetic Studies on Mental Disorders and the NIDA Center for Genetic Studies (both with Dr. John Rice), and Director the NIDDK Genetics Repository and the NIAAA/COGA Repository. The Centers also help PIs to design population-based studies so that they might be done in the most efficient and cost-effective manner.
Andrew I. Brooks, PhD
Andrew I. Brooks is an Associate Professor in the Department of Genetics and the Associate Director for Technology Development at Rutgers University. He also is an Associate Professor of Environmental and OccupationalMedicine and Director, Bionomic Research and Technology Center at the University of Medicine and Dentistry, New Jersey (UMDNJ). Previously, Dr. Brooks was the Director of the Functional Genomics Center, Director of the Microarray Analysis Core and Academy for Medical Development and Collboration (AMDeC) Microarray Resource Center at the University of Rochester Medical School. Dr. Brooks obtained his PhD in Microbiology and Immunology from the University of Rochester Medical School in Rochester, NY. He is the author of over 45 research publications in the area of molecular medicine and gene therapy. Dr. Brooks is the Director of Technology, and is credited with creating a novel LIMS system for the RUCDR with the StarLIMS company. Dr. Brooks is also the Director of the Nucleic Acid Services and Analysis Lab and serves as the Project Director for the AMDeC Collection. Dr. Brooks supervises cell line identity and mycoplasma testing, DNA distributions. He develops and implements new analytical procedures as needed. His current research interests include gene expression and microarray data analysis.
Linda Brzustowicz, MD
Linda Brzustowicz earned her AB from Harvard-Ratcliffe College and her MD from Columbia University College for Physicians and Surgeons. Dr. Brustowicz completed her medical residency in pediatrics at Rhode Island Hospital (Brown University) and fellowships in molecular genetics and psychiatry at New York State Psychiatric Institute. Dr. Brzustowicz is a Professor in the Department of Genetics. Her research applies techniques of statistical genetics to understand gene function in normal and pathologic states in clinical neuroscience. Specifically, her group focuses on autism, schizophrenia and specific language impairment (SLI). Their work includes gene expression studies, statistical analysis and genotyping for association and linkage studies, and comparative genomic analysis. Dr. Brzustowicz also looks at the role of microRNAs in the gene expression control in the brain and high-throughput genotyping techniques. Dr. Brzustowicz is the author of over 70 peer-reviewed publications. Dr. Linda Brzustowicz is the new Chair for the Department of Genetics.
Sanghamitra “Mitu” Pati, MA, MBA
Mitu Pati is the HGI Director of Finance and has overall responsibility for financial activities of the Institute. Prior to joining the HGI, she was the Director of Finance at the Indiana University School of Health and Rehabilitation Sciences where she was responsible for the overall financial and grant activities such as pre-award and post-award administration of the school. She also worked as Business Manager at the School of Allied Healthat the Indiana University School of Medicine. Her expertise includes working on PeopleSoft and other legacy systems. She works directly with the PI and Project Directors on budgeting and financial planning of program activities. She has over twelve years of experience in overseeing financial aspects of major government grants, contracts, and cooperative agreements.
Sheri Lumpkin is the Assistant to the Executive Director of the Human Genetics Institute of New Jersey. She can be contacted at email@example.com or (732) 445-1027 ext. 40042.
For current employment opportunities in the Human Genetics Institute of New Jersey, including the Rutgers University Department of Genetics, Rutgers University Cell and DNA Repository, and the Bionomics Research and Technology Center, visit the Rutgers University Human Resources Website here.