Novel insights into human pluripotency and neural induction

When

Fri, Jan 29, 2016 12:00 pmuntilFri, Jan 29, 2016 1:00 pm

Where

Life Sciences Building Auditorium
145 Bevier Road
Piscataway
NJ
08854

Contact

(732) 445-1027 x 40071

Event Actions

About

Ilyas SingeƧ, M.D., Ph.D.
Head, Stem Cell Research
National Institutes of Health Center for Regenerative Medicine
Stem Cell Translation Laboratory
National Center for Advancing Translational Sciences (NCATS)
Rockville, MD

The seminar will describe and analyze the largest phospho-proteomic dataset generated so far using OCT4+ pluripotent stem cells and PAX6+ multipotent neural stem cells derived by using a highly defined neural induction strategy. Direct quantitative comparison of these two distinct developmental states identified novel regulators and mechanisms of early fate choice that are relevant for systematic analyses of later-stage neural development and cell engineering.