Genetic epidemiology of neuropsychiatric disorders: Understanding the comorbidity

When

Mon, Sep 21, 2015 12:00 pmuntilMon, Sep 21, 2015 1:00 pm

Where

Life Sciences Building Auditorium
145 Bevier Road
Piscataway
NJ
08854

Contact

(732) 445-3331

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About

GARY HEIMAN, PH.D.
ASSISTANT PROFESSOR
DEPARTMENT OF GENETICS
RUTGERS UNIVERSITY

Individuals with a neurological disorder (e.g., Tourette’s disorder, epilepsy, and Parkinson’s disease), often
also have a psychiatric disorder (e.g., depression, anxiety, or obsessive-compulsive disorder). The causes of this comorbidity remain unclear. While often unrecognized and untreated, having both disorders can have a profound impact on the individual including a lower quality of life, a higher risk for suicide, and a worse disease course. The focus of my research program is to use genetic data to understand the cause for the comorbidity for different neurological disorders. In particular, my studies test the hypothesis that the comorbidity is due, in part, to a shared genetic susceptibility. In this talk, I will briefly discuss my studies on mood disorders in epilepsy and in Parkinson’s disease. Then, I will devote most of the presentation reviewing our work to understand the genetic architecture of Tourette’s disorder and its associated comorbid conditions, including obsessive-compulsive disorder and attention deficit hyperactivity disorder.