Monitoring Clonal Dynamics of Cancer in the Clinic

When

Mon, Feb 03, 2020 12:00 pmuntilMon, Feb 03, 2020 1:00 pm

Where

Life Sciences Building Auditorium
145 Bevier Road
Piscataway
NJ
08854

Contact

(848) 445-2011

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About

Shridar Ganesan, Ph.D., MD 
Professor of Medicine and Pharmacology
Assoc. Director for Translational Science
Chief, Section of Molecular Oncology 
Rutgers, Cancer Institute of New Jersey

Advances in sequencing technology allow both high-depth analysis of primary tumor specimens to guide treatment and monitoring of tumor evolution under targeted treatment through serial analysis of ctDNA in plasma. This ability to monitor clonal evolution of cancer under selection pressure of treatment in the clinic has led to new insights into cancer biology and mechanisms of primary and acquired resistance.  Illustrative cases and new methods to analyze and interpret high-depth clinical tumor sequencing data will be presented and discussed.