Seminars

Subcategories

I will discuss two topics. The first is mitotic checkpoint signaling, taking advantage of a technique that we developed for rapidly recruiting checkpoint proteins to kinetochores by chemically-induced dimerization. The second is biased chromosome segregation in meiosis, also known as meiotic drive, which has fascinating implications for chromosome evolution.

Starts Mon, Nov 25, 2013 12:00 pm
Ends Mon, Nov 25, 2013 1:00 pm
Location Life Sciences Building Auditorium

Oncogenic events initiate cancer cells with different kinetics that determine initial tumor progression dynamics. We developed a quantitative model that tracks the temporal evolution of the malignant subpopulation of cancer stem cells. We discuss evolution of the most aggressive set of cancer stem cell kinetics that drives tumors into malignancy regardless of their founding properties, and propose potential treatment targets to dwarf tumor growth.

Starts Mon, Nov 11, 2013 12:00 pm
Ends Mon, Nov 11, 2013 1:00 pm
Location Life Sciences Building Auditorium

Repair of DNA breaks with the appropriate chromosomal template is critical to maintain genomic integrity and to promote proper chromosome segregation during meiosis, the specialized cell division that generates sperm and eggs. My talk will focus on how meiotic chromosome structures both control and respond to particular DNA repair outcomes.

Starts Mon, Oct 28, 2013 12:00 pm
Ends Mon, Oct 28, 2013 1:00 pm
Location Life Sciences Building Auditorium

Dr. Andrew Brooks

RUCDR Infinite Biologics

Topic: RUCDR Services

Starts Mon, Oct 14, 2013 12:00 pm
Ends Mon, Oct 14, 2013 1:00 pm

Current advances in next-generation based sequencing of human cancer and molecularly targeted therapy will be presented. Early results from a genomic-sequencing trial of rare/poor prognosis cancers at CINJ will be used to highlight the promise and challenges of applying genomic profiling to the clinic.

Starts Mon, Sep 30, 2013 12:00 pm
Ends Mon, Sep 30, 2013 1:00 pm
Location Life Sciences Building Auditorium