My research group applies the techniques of molecular and statistical genetics to approach clinically relevant problems in neuroscience, with the ultimate goal of understanding gene function in both the pathologic and normal states. We are currently studying the genetics of schizophrenia, autism, and psychiatric symptomatology. Work currently or previously directly conducted by my group includes development of phenotype definitions, subject recruitment and assessment, genotyping and statistical analysis for linkage and association studies, comparative genomic analysis, and gene expression studies. Other areas of particular interest include the role of microRNAs in the control of gene expression in the human brain and enhancements to moderately high throughput genotyping technologies.
- "NIMH Center for Collaborative Genetic Studies on Mental Disorders" NIMH (U24 MH068457) Tischfield/Brzustowicz Co-Principal Investigator
- "Elucidating Genetic Components of Autism and Related Disorders" New Jersey Governors Council for Medical Research and Treatment of Autism (CAUT12APS006) Linda Brzustowicz Principal Investigator
- "Elucidating Genetic Components of Autism and Co-occurring ADHD using Whole Genome Sequencing" New Jersey Governors Council for Medical Research and Treatment of Autism (CAUT19APL028) Xing/Brzustowicz Co-Principal Investigator